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Riccardo Nifosì

CNR Researcher

tel. +39 050 509412

fax +39 050 509417

riccardo.nifosinano.cnr .it


Piazza San Silvestro 12
56127 PISA

Research interests

1. Photophysical properties of Fluorescent Proteins
2. Computational modeling and design of molecular vectors for intracellular delivery

Biographical sketch

1992-1997: Undergraduate fellowship from the Scuola Normale Superiore Pisa, Italy
1997: Laurea (MSc) in Physics from the University of Pisa, Italy. Supervisor: Prof. M. P. Tosi
2004: PhD in Physics from the Scuola Normale Superiore Pisa, Italy. Supervisors: Prof. F. Beltram and Dott. V. Tozzini. Title of the thesis: "Molecular Mechanisms of Green Fluorescent Protein Photophysics".

Professional experience
Jan 2002 - Jul 2004: Scholarship of the INFM on "Modeling Green Fluorescent Proteins with classical and ab-initio molecular dynamics".
Jul 2004 -Feb 2009: Tenure track research scientist at CNR-INFM NEST, Pisa, Italy
Feb 2009 - now: Research scientist at CNR-NANO NEST, Pisa, Italy

Selected publications

P Amat, R Nifosì,"Spectral 'Fine' Tuning in Fluorescent Proteins: The Case of the GFP-Like Chromophore in the Anionic Protonation State" J Chem Theory Comput 9, 497 (2013).

F Salomone, F Cardarelli, M Di Luca, C Boccardi, R Nifosì, G Bardi, L Di Bari, M Serresi, F Beltram, "A novel chimeric cell-penetrating peptide with membrane-disruptive properties for efficient endosomal escape", J Control Release 163, 293 (2012)

V Voliani, F Ricci, G Signore, R Nifosì, S. Luin, F. Beltram, "Multiphoton Molecular Photorelease in Click-Chemistry Functionalized Gold Nanoparticles" Small 7, 3271 (2011).

G Signore, R Nifosì, A Lorenzo, S Barbara, B Ranieri, “Polarity-sensitive coumarins tailored to live cell imaging” J Am Chem Soc 132, 1276 (2010).

R Nifosì , Y Luo, "Origin of the Anomalous Two-Photon Absorption in Fluorescent Protein DsRed", J Phys Chem B (Letter) 111, 505 (2007).

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