Marco Cecchini

Short Bio

Born in Italy in 1975, he received his Master degree in Physics from the Physics Department of the University of Pisa (Italy) in 1999, and PhD in Condensed Matter Physics from the Scuola Normale Superiore (Italy) in 2006. Currently, he is senior researcher and member of the scientific council of the Nanoscience Institute (Pisa, Italy) of the Italian National Research Council (CNR), CTO of INTA srl (a joint spin-off company of the CNR and Scuola Normale Superiore) and Lecturer of Biomaterial Science at the University of Pisa (Biology Department, Laurea Degree Course in Biotechnology).

Research Interests

Development of nanomaterials for brain pathologies and nerve regeneration; development of surface-acoustic-wave devices for microfluidics and sensing applications.

Selected Recent Projects

FISR 2019, Grant FISR2019-03020, “ Wine and Oil Analysis 4.0: development of a Lab-On-Chip with remote connectivity”
Regione Toscana, Bando Ricerca Salute 2018, “The Omics Sciences Against Osteosarcoma – TOSCANO”
Regione Toscana, Bando Ricerca Salute 2018, “Neurodegenerative disorders throughout the lifespan. Autophagy-dependent biomarkers for trial readiness from infantile neuronal ceroid-lipofuscinoses to senile dementias – DEMAGING”
European Leukodystrophy Association (ELA) International Grant, ELA 2019-008I2 “nanoERT – Nanoparticle based Enzyme Replacement Therapy for the treatment of Krabbe disease: a pre-clinical study in the Twitcher Mouse”
Fondazione Cassa di Risparmio di Lucca “SAWine: Lab-on-a-Chip based on Surface Acoustic Waves for precision oenology”
European Leukodystrophy Association (ELA) International Fellowship Grant, ELA 2018-008F2 “Pre-clinical testing of single and combined autophagy modulation by Lithium and Rapamycin in Globoid Cell Leukodystrophy”

Selected Publications

"Glial-fibrillary-acidic-protein (GFAP) biomarker detection in serum-matrix: Functionalization strategies and detection by an ultra-high-frequency surface-acoustic-wave (UHF-SAW) lab-on-chip", M. Agostini, F. Amato, ML. Vieri, G. Greco, I. Tonazzini, L. Baroncelli, M. Caleo, E. Vannini, M. Santi, G. Signore, and M. Cecchini, Biosensors and Bioelectronics 172, 112774 (2021).

"Ultra-high-frequency Love surface acoustic wave device for real-time sensing applications", G. Greco, M. Agostini, and M. Cecchini, IEEE Access 8, 112507-112514 (2020).

"Brain-targeted enzyme-loaded nanoparticles: A breach through the blood-brain barrier for enzyme replacement therapy in Krabbe disease", A. Del Grosso, M. Galliani, L. Angella, M. Santi, I. Tonazzini, G. Parlanti, G. Signore, and M. Cecchini, Science Advances5, no. 11, eaax7462, DOI: 10.1126/sciadv.aax7462 (2019).