Giorgia Brancolini

Short Bio

CNR Researcher working for a decade on multi-scale modeling of Interfaces between Biomolecules and Nanomaterials, Biological Macromolecules and Proteins Folding Dynamics, using methods ranging from ab initio calculations to atomistic and coarse grained molecular dynamics. Currently PI of a PRIN2020 National Project (LS1), she was participant of an H2020 ERC Consolidator grant (PE4) and PI of a CNR SEED Project (GAE PUSEED04). PI of several supercomputing projects (e.g. Oak Ridge (USA): CNMS2020-B-00433; HPC-Europa: 2019/ HPC177BQ0O). She teaches at the Department of Physics Univ. Modena currently “Chemical Physics of Biomolecules”, Master's degree in Physics. She is the author of ~40 peer-review papers, with h factor 17 (source: scopus/scholar), and contributed to ~20 conferences with invited talks.

Research Interests

Development of Anti-SARS-Cov2 Therapeutic Strategies; Design of Biosensors; Functionalized Metal Nanoparticles as Nanotheranostic Agents; Intrinsically Disordered Proteins.


Selected Recent Projects

2021-2024: PI of RU PRIN2020 Project “Early Phase Preclinical Development of PACECOR, a Mutation-Independent Anti-SARS-Co2 Therapeutic Strategy” (in progress)
2016-2018: PI of SEED CNR national project (GAE PUSEED04): “LOPE-DeveLopment of a Coarse Grained Model for Nanoparticle-Protein IntEractions.” CNR Seed’s Project. Granted Budget: 15.000 Euro. PI G. Brancolini [Development of a CG methodology to study the Nanoparticle-Protein interactions]

2020-2022: PI of Supercomputing project “Molecular strategies to inhibit the COVID-19-cell interaction” at ORNL, USA. CNMS2020-B-00433. Granted 1.000.000 CPU hours (2 years). [Developing an in silico strategy to design biological inhibitors of SARS-CoV-2]

Selected Publications

G. Brancolini, V. M. Rotello, and S. Corni, Role of Ionic Strength in the Formation of Stable Supramolecular Nanoparticle–Protein Conjugates for Biosensing, Int. J. Mol. Sci. (2022)


S.Dutta, S Corni, and G Brancolini, Atomistic Simulations of Functionalized Nano-Materials for Biosensors Applications, Int J Mol Sci (2022)


M. Ray, G. Brancolini, D.C. Luther, Z. Jiang, R. Cao-Milán, A.M. Cuadros, A. Burden, V. Clark, S. Rana, R. Mout, R.F. Landis, S. Corni, and V.M. Rotello, High affinity protein surface binding through co-engineering of nanoparticles and proteins,  Nanoscale (2022)


S. Dutta, S. Corni, and G. Brancolini, Molecular Dynamics Simulations of a Catalytic Multivalent Peptide–Nanoparticle Complex, Int J Mol Sci. (2021)


G. Brancolini, H. Lopez, S. Corni, and V. Tozzini, Low-resolution models for the interaction dynamics of coated gold nanoparticles with β2-microglobulin, Int J Mol Sci (2019)


G. Brancolini, V. Tozzini, Building Minimalist Models for Functionalized Metal Nanoparticles, Front Mol Biosci (2019)


V. Tozzini and G. Brancolini, Coarse Grained and Multi-scale modeling of biofunctionalized nanoparticles, Curr Opin Colloid In (2019)


G. Brancolini, L. Bellucci, M.C. Maschio, R. Di Felice, and S. Corni, Protein and peptide interactions with nanostructured gold surfaces: a challenge for nanoscience, Curr Opin Colloid In (2019)


G. Brancolini, M.C. Maschio, C. Cantarutti, A. Corazza, F. Fogolari, S. Corni, G. Esposito, Citrate stabilized Gold Nanoparticles interfere with Amyloid Fibril formation: D76N and N6 Variants, Nanoscale (2018)


G. Brancolini, A. Corazza, M. Vuano, F. Fogolari, M.C. Mimmi, V. Bellotti, M. Stoppini, S. Corni, and G. Esposito, Probing the Influence of Citrate-Capped Gold Nanoparticles on an Amyloidogenic Protein, ACS Nano 2015